In allusion to the problems that the distance of so many instruments in the laboratory interference cancellation test system is far and the operation in the process of measurement is tedious and repetitive, this article introduces the way of developing an automatic test system based on virtual instrument software development platform—LabVIEW and LXI bus technique. According to the practical demand, the system can successfully communicate with the instruments and realizes the functions of instruments parameter setting, waveform acquisition and data preservation. It can complete automatic filter in different conditions. The experiment results prove that the system has good humancomputer interaction interface.it runs well with highly automation operation and good expansibility, and has allright application foreground.