Aiming at researching the problems of operating control reliability of automatic industrial washing machine, a control system based on PLC、frequency converter is proposed. The control system adopts Siemens S7-200 CPU224 PLC as the core controller, and cooperates with the inverter and industrial touch screen to realize the functions of operation control, operation and monitoring of the fully automatic industrial washing machine. This article details the hardware design, selection and software programming and configuration of the system. Through functional verification, the control system of this fully automatic industrial washing machine can fully meet the running requirements, and the reliability and flexibility of operation have been improved.